This one's a new book (2010), but also first in a new series of supernatural/vampire books. It's set in the now, but a slightly different "now" - one where the supernatural is commonplace and has become a very real threat. Everyone gets tested in grade school to determine their level of extra-sensory talents ... as much to determine their threat level as to help train their skills.
While the main character, Celia Graves, is a professional bodyguard, this book is really more squarely in the detective genre. When Celia is attacked and bitten by a vampire while on a big-dollar guard job, she becomes an "abomination:" not vampire, but not wholly human anymore either. She's determined to hunt down her sire and make him pay; that quest is complicated by both her physical changes and the fact that her attack seems to be part of a much larger evil.
I enjoyed the book immensely and pretty much read it in a sitting. Celia's tough but still feminine, and the supporting characters and their unusual skills kept me interested. While the book resolves its main plot, it also leaves an interesting cliff-hanger and a host of challenges and mysteries about Celia to carry us into the next book.